Multiple leisons in 70%
99.7%. Cervical ca related to HPV
HPV double DNA
Early gene E late gene L. Vaccine L1 gene
HPV vaccine 16 18 responsible 70% Ca cervix
Quadrivalent vaccine Gardasil 6 11 16 18
9-26 yrs
Cervarix
How long does immunization work?
Should men be vaccinated?
>120 types HPV
E6/E7 gene
Smoking cessation engouages regression of CIN
Barrier methods regression of CIN
circumcision ?
Recall system reduction in incidence 60%
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