Friday, 27 February 2009

Genital cancer needs editing

Multiple leisons in 70%
99.7%. Cervical ca related to HPV


HPV double DNA


Early gene E late gene L. Vaccine L1 gene
HPV vaccine 16 18 responsible 70% Ca cervix

Quadrivalent vaccine Gardasil 6 11 16 18
9-26 yrs
Cervarix

How long does immunization work?
Should men be vaccinated?





>120 types HPV

E6/E7 gene

Smoking cessation engouages regression of CIN


Barrier methods regression of CIN

circumcision ?

Recall system reduction in incidence 60%

Genital cancer needs editing

Multiple leisons in 70%
99.7%. Cervical ca related to HPV


HPV double DNA


Early gene E late gene L. Vaccine L1 gene
HPV vaccine 16 18 responsible 70% Ca cervix

Quadrivalent vaccine Gardasil 6 11 16 18
9-26 yrs
Cervarix

How long does immunization work?
Should men be vaccinated?





>120 types HPV

E6/E7 gene

Smoking cessation engouages regression of CIN


Barrier methods regression of CIN

circumcision ?

Recall system reduction in incidence 60%

Amenorrhora(Needs edit)

With secondary sexual characteristic
With out secondary sexual charecterstic
Excess androgen
Absence of uterus


Rockintasy 30-40% urinary tract abnormalities
Can have their children-surrogate mother


Adolescent menstrual dysfuction may be worries about pregnancy STD contraception

'Pseudo'haemaphrodism

XY females
Pure gonadal dysfenesis
Enzymatic failure
End organ insensitivity
Exogenous hormones-CAH


Teen age pregnancy (needs editing)

I'M highest teenage pregnancy rate in Western world.
Definition 13 yrs-below 18 yrs in gov publication includes 18-19 yrs.

Teen age pregnancy is cause and consequence of social exclusion.

Problems-medical social education

Medical hypertension anaemia placental abruption prematurity sudden infant death syndrome

Social deprivation low self esteem low education

Friday, 23 January 2009

Infertility

Definitions unable to conceive >12 months but epidemiologist tend to define as >24 months

Fertility depends on frequency of intercourse
Ovulation induction kit decreases the fertility


Use of lubricants decreases the sperm motility
Risk of Infertility
PID * 1 7
PID*3 19

Semen analysis if poor repeat in 72 days


Chlamydia antibodies

Basal body temperature not recommended.Marital dysharmony

Female genital mutilation

WHO definitions whole or part
Type 1-4
Type 3 partial closing of vagina
Type 4 corrosives


Africa Asia not faith related Christian Muslim

Immediate complications

Infection
Bleeding
Urinary retention
Death


Post op positioning leg finding

Longterm consequences



Obstetrics
Type 2 &3
PPH
Obstetrics labour


UK

Shock amongst carers
Painful examinations
Analgesia regional
Episiotomy anteriorly not laterally

Female Genital Multilation Act 2003