A powerpoint explaining Conn's syndrome
Image explaining Renin-Angiotensin-Aldosterone cascade
(III)Adrenal carcinoma rare
(II)radioactive selenium cholesterol test should be delayed until after delivery.
(III)suppressed renin activity
(IV) increased plasma aldosterone
(V)MRI of abdomen
Multidisciplinary care involving Obstetrician,Endocrinologist and Physicians.
Hypertension should be controlled by anti hypertensives (labetolol,methyldopa,nifidipine)
Hypokalaemia managed by
(A) Potassium supplementation
(B)Potassium sparing diuretics Amelioride is preferred over spironolactone because of anti androgenic property of the latter that could lead to feminizing a male fetus.
Surgery is effective in adrenal adenoma or carcinoma but the value is limited in adrenal hyperplasia.Surgery could be postponed until after delivery.If surgery is indicated for
(i) Fluid & electrolyte balance should be maintained.
(I) Pituitary and adrenal disorders complicating pregnancy:Chandraharan, Edwin; Arulkumaran, Sabaratnam
(2)Nelson-Piercy C. Handbook of obstetric medicine. Taylor & Francis; 2002.
(3)Swiet MD. Medical disorders in obstetric practice. Wiley-Blackwell; 2002.
(5)Primary aldosteronism in pregnancy.Matsumoto J, Miyake H, Isozaki T, Koshino T, Araki T.J Nippon Med Sch. 2000 Aug;67(4):275-9